Evaluation of the stimulatory and inhibitory effects of Malva sylvestris leaf extract on some beneficial and pathogenic bacteria from the colon

The aim of the present study was to evaluate stimulatory and inhibitory effects Malva sylvestris leaf extract on some selected beneficial pathogenic bacteria from colon form a presupposition its efficacy intestinal health. sensitivity bacterial strains M. tested by broth dilution method in anaerobic cabinet. stimulated growth Bifidobacterium bifidum species starting 0.06 mg/mL dose (P<0.05). same effect observed for other infantis Lactobacillus acidophilus 0.125 (P<0.05) that more obvious B. infantis. On hand, did not have any casei up 4 dose. also had potential activity against Escherichia coli, Clostridium perfringens, Staphylococcus aureus 0.25, 2, concentrations respectively 8 (MIC; minimal concentration) completely inhibited Fusobacterium nucleatum (P<0.05), enteropathogen, which is associated with colorectal cancer. It concluded at 0.06-8 could favorable since selectively promoted most species’ this range while it or ones. Investigating testing vivo effectiveness will contribute better understanding microbiota